DisProt 2023_12 - New thematic dataset of condensates-related intrinsically disordered proteins

DisProt team provides a collection of manually curated proteins driving liquid-liquid phase separation (LLPS) and Membraneless Organelles (MLO) related protein formation.

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DisProt 2023_06 - New thematic dataset of Intrinsically Disordered Proteins related to Neurodevelopmental disorders (NDDs)

DisProt curation team is proud to announce the new thematic dataset, “NDDs-related proteins”, with the important aim to define the role and abundance of intrinsically disordered proteins in Neurodevelopmental diseases.

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DisProt 2022_12 - Release featuring a thematic dataset of neglected tropical diseases IDPs and IDRs

The DisProt curation team is pleased to release a new thematic dataset portraying “Neglected tropical diseases proteins”, describing the presence and role of IDPs and IDRs in pathogens causative of these diseases.

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Biocuration in DisProt: online eLearning courses and submission form

The “Biocuration in DisProt” page (https://disprot.org/biocuration) has been updated with the addition of two new features: i) an eLearning course on literature curation of IDPs for DisProt biocurators and ii) a submission form for DisProt external users to contribute new annotations.

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Training materials for DisProt users

New training materials are available for DisProt users: a protocol - available in Current Protocols in Bioinformatics - describing how to explore manually curated annotations of intrinsically disordered proteins with DisProt, and two webinars - available in TeSS, the ELIXIR Training Portal - describing how...

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DisProt 2022_06 - Release featuring the “autophagy-related proteins” and “cancer-related proteins” datasets

This release of DisProt features two new thematic datasets, “autophagy-related proteins” and “cancer-related proteins”, exploring the role played by intrinsically disordered regions (IDRs) and proteins (IDPs) in two main biological areas - autophagy and cancer.

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DisProt 2022_03 - a technical release

We completed the Gene Ontology (GO) integration

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DisProt 2021_12 - Thematic release featuring a dataset of IDPs and IDRs in “viral proteins”

DisProt 2021_12 - Thematic release featuring a dataset of IDPs and IDRs in “viral proteins”

The DisProt curation team is pleased to publish a new release featuring the third thematic DisProt dataset, “viral proteins”, exploring the role of IDPs and IDRs in the context of viral proteins.

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DisProt partner of the GO consortium

We are proud to announce that DisProt is now a partner of the GO consortium.

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DisProt 2021_08 - Integration of ECO and GO ontologies

DisProt 2021_08 - Integration of ECO and GO ontologies

DisProt adopted two dedicated and stable ontologies - the Gene Ontology and the Evidence and Conclusion Ontology - to improve the representation of interactions, disorder functions and describe the experimental methods used to assess disorder.

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The new DisProt user interface with an improved user experience

We have simplified the DisProt interface and improved its loading speed for a better user experience

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DisProt 2021_06 - Thematic release featuring a dataset of “extracellular matrix proteins”, and several revised and new entries

DisProt 2021_06 - Thematic release featuring a dataset of “extracellular matrix proteins”, and several revised and new entries

The DisProt curation team is pleased to report a new release featuring the second thematic DisProt dataset: “extracellular matrix proteins”, describing the role of IDPs in this network within the tissues. At the same time, we have continued the process of reviewing and updating entries...

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DisProt 2020_12 - first thematic release featuring a dataset of "unicellular toxins and antitoxins", revised and new entries

The DisProt curation team is proud to announce a new in-between-publication release featuring the first thematic DisProt dataset: "unicellular toxins and antitoxins", consisting of 23 new entries and 25 already existing entries that have been fully reannotated and updated. This is the first thematic release...

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DisProt 2020_06 - new viral proteins, updated home page examples and other entries

The DisProt curation team is excited to announce the new release featuring newly added proteins related to SARS-CoV-2 as a response to the global pandemic, as well as revised and updated home page examples and previously published entries in an effort to continuously improve curation...

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DisProt blog - welcome

This blog has been created to advertise updates and narratives on each new release of DisProt.

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