Biocuration in DisProt: online eLearning courses and submission form
The “Biocuration in DisProt” page (https://disprot.org/biocuration) has been updated with the addition of two new features: i) an eLearning course on literature curation of IDPs for DisProt biocurators and ii) a submission form for DisProt external users to contribute new annotations.Written on Dec 1, 2022, by Federica Quaglia and Victoria Nugnes.
eLearning course for DisProt biocurators
Submission form for DisProt external users
An interactive annotation form has been made available to external users to contribute new annotations. The form is compliant with the “MIADE metadata guidelines: Minimum Information About a Disorder Experiment” (https://doi.org/10.1101/2022.07.12.495092) for the annotation of IDP experimental data.
The form allows users to specify the UniProt identifier of the protein they are annotating, along with optional information such as Name, email address, ORCID identifier and Comments. The interactive form includes three sections. In the first section users are required to add a PubMed identifier of the protein under annotation, an Evidence and Conclusion Ontology (ECO) term corresponding to the experimental technique used to characterize the IDP/IDR in the publication, the start and end residues of the IDR (Boundaries) as described in the publication. In the second section, users can select the evidence aspect of the IDR - structural state (IDPO), structural transition (IDPO), function (GO) and function (IDPO) - as well as cross references and statements from the publication that describe the annotated IDR. Finally, the third and last section allows the users to add MIADE annotations by selecting one (or more) additional fields among sequence construct, experimental conditions and experimental components.